What are some typical ways to socialize, either with local people or with other expatriates? Are there groups or clubs that you can recommend?
Get out there. If you expect others to knock on your door you are guaranteed to have a very boring life in Santiago. Join Meet-up groups aligned to your hobbies. Here is a reference for you: I have yet to be invited to the home of a Chilean after being here for two years. - Jun 2019
There's lots of restaurant, bars, discos, concerts of all kinds, movies, plays, ballet, art exhibits. Every year there are a ton of ferias during the summer from food/beer to clothing/shoes. Tons of social things, there's the hash if you know what that is and tons of other activities that you can just join to learn. - Feb 2016
Eat out, entertain in, movies, there are theater events available, day trips. - Nov 2014
Hanging out in Bellavista, salsa clubs, movies, restaurants. - Oct 2014
There are lots of great restaurants, lots of theatres, lots of concerts. There is always a lot going on. You will not have trouble keeping busy. - Sep 2011
There are all different types of entertainment in Santiago. Depends on the group mix of people at post. - Jul 2010
The usual in a large, cosmopolitan city. - Apr 2009