What is your home city/country? How long is the trip to post from there, with what connections?
I'm from New Jersey by way of Virginia. There are a few connections that we use most often: Djibouti -> Addis Ababa -> DC or Djibouti -> Paris -> DC. There is also a connection through Doha. - Jun 14, 2016
New Mexico. There are several ways to get to the U.S. from Djibouti. Air France to CDG is my favorite but only flies once a week from here. Ethiopian Air is the most convenient but I'm not a fan of that airline. Poor maintenance and a confused staff running the airport in Addis but they received "Best in Africa" awards (not from me). There are also connections through Dubai and Doha. Fly Dubai lost my luggage in both directions on one trip but the United connection to DC wasn't bad. Qatar is supposed to be nice but I haven't flown it. Trips are expensive out of Djibouti but available and people here make trips to India, Thailand and to Mauritius and seem to think the connections are not bad. - Aug 14, 2015
USA. Multiple routes are available, but none is direct. The cheapest and fastest is usually via Ethiopian Air (Djibouti to Addis, Addis to DC), but for official travel one flies through Europe. - Feb 28, 2013
From Washington, D.C., the trip can take up to 30 hours if you are flying via Paris on Air France (that flight from Paris to Djibouti flies once a week), and the layover in Paris is 12 hours. You can also fly to Djibouti via Addis, Nairobi, and Dubai. Depending on the route and timing of the flights, you may have to overnight. - Apr 13, 2010